Blog

Notes on the leaf, and using it well.

Plain-spoken writing about kratom and 7OH: the science, the responsible-use practices, and the transparency the category usually skips.

1–10 of 70
9 min

Reference Material Certification: A Canadian Lab Guide

Discover the essentials of reference material certification and learn how it validates certified reference materials in Canadian labs.

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13 min

MGM-15 vs 7-OH: Key Differences, Potency and Risks

Compare MGM-15 vs 7-OH: what research says about their differences, potency, risks and legal status, plus signs of misuse and support options.

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15 min

Dissolution Media Selection: Start at pH 1.2, Add Only What You Need

Choose dissolution media with a fit for purpose method: start with pH 1.2 and 6.8 buffers, then add surfactant only when solubility data justify the choice.

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16 min

Clinicians & researchers: 7-hydroxymitragynine pharmacology

Evidence-first briefing for clinicians and researchers: receptor affinities, human PK (CYP3A4 role, 1.77 h Tmax), naloxone-reversible respiratory risk,...

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10 min

University Procurement of 7OH in Canada: What Labs Should Know

Thinking of buying 7OH for a university lab in Canada? Here is the news, the legal picture, the paperwork questions and what to ask any supplier first.

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12 min

7-OH Comparator Standards: What Labs Should Check First

7-OH is back in the headlines. Here's what a comparator standard is, what a certificate of analysis should show, and what Canadian labs should confirm first.

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15 min

Health Canada Playbook: Research Chemical Compliance for Canadian Labs

Canada first compliance for research labs. Use an 8 item checklist, 5 step workflow and supplier documents aligned with Health Canada.

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10 min

Three Nonnegotiables Labs Need for 7-Hydroxymitragynine Tablet Testing

Labs: secure ISO 17034 CRMs with NMR COAs, run multicriteria LC-MS/MS, and document LLOQ to HQC calibration for defensible 7-OH tablet testing.

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10 min

Labs: 7-OH Tablet Strengths 15, 30, 50 mg for COA & Validation

Compliance guide for labs: 7-OH tablet strengths 15, 30, 50 mg. COA checks, sourcing, storage, and validation steps to protect analytical results.

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11 min

Speciociliatine Reference Standard: What Labs Should Require

How to choose and use a speciociliatine reference standard in Canada: purity, CRM versus analytical grade, diastereomer separation, COAs and legal context.

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Responsible-use notes, occasionally.

New drops and the occasional well-researched note. No spam.