Sep 2026 · 9 min
Reference Material Certification: A Canadian Lab Guide
Discover the essentials of reference material certification and learn how it validates certified reference materials in Canadian labs.
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Notes on the leaf, and using it well.
Plain-spoken writing about kratom and 7OH: the science, the responsible-use practices, and the transparency the category usually skips.
11–20 of 70
13 min
Mitragynine Tablet Standards: What Canadian Labs Should Demand
Scheduling news is moving fast. Here's what real mitragynine tablet standards look like for Canadian labs: CoAs, validated methods, reference materials and licences.
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14 min
Method Developers: Choose Dissolution Apparatus by Failure Mode
Match dissolution apparatus to failure modes and document choices for review. See how dosage form, solubility, and formulation behavior shape USP selection.
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12 min
7OH Tablet Disintegration: What the Headlines Miss
Why 7OH tablets are in the news, what disintegration testing means in a lab, and what U.S. and Canadian rules mean for researchers in 2026.
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12 min
Analytical Alkaloid Orders for Canadian Labs: Avoid a 70 Day Reset
See how Canadian labs can source alkaloids for research, check supplier documents, choose a Health Canada pathway, and avoid a 70 day filing reset.
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13 min
7OH Tablet Excipients: What Else Is in a Research Tablet
What excipients do 7OH research tablets contain, and why do binders, fillers and lubricants matter for analytical work? A Canadian lab guide with checks.
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11 min
Speciogynine Reference Standard: What Labs Should Check
How to choose and use a speciogynine reference standard: CRM status, ISO 17034, uncertainty, and why separating it from mitragynine matters in LC-MS/MS.
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13 min
Matrix-Matched 7OH Standards: A Practical Guide for Labs
How to build matrix-matched 7OH standards for LC-MS/MS: blank matrix, internal standards, calibration ranges, matrix factors and what to demand from suppliers.
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14 min
7OH Spiking Solutions for Analytical Labs: A Practical Guide
How to prepare, verify and use 7-hydroxymitragynine spiking solutions for LC-MS/MS recovery, calibration and matrix-effect work in Canadian research labs.
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7 min
Isopaynantheine Reference Standard: Why MS/MS Alone Can Mislead
See how an isopaynantheine reference standard supports identification, why MS/MS alone can fail, and when chromatography or NMR confirms the compound.
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8 min
7OH Lab Comparisons: Fewer False Positives, Clearer Scores
Compare 7OH results across labs with shared preparation, reference materials, and scoring rules to catch false positives and limit assigned value uncertainty.
Read →Responsible-use notes, occasionally.
New drops and the occasional well-researched note. No spam.
